靈芝裡蘊藏的三萜類之豐富，科學家挖掘了近四十年還挖掘不完，目前已經知道的就快二百種，作用巧妙也不盡相同。

九州大學發表的研究則指出，萃取自靈芝子實體的靈芝酸混合物，可抑制壞骨細胞的分化。對於像骨質疏鬆症這種因「壞骨細胞」多過「造骨細胞」而使骨骼過度流失的疾病來說，壞骨細胞的抑制必可減輕病情的惡化。

（以上文章原刊登於49期《健康靈芝》雜誌）4495

Planta Med. 2010 Feb;76(2):137-9. Epub 2009 Aug 10.
Ganoderic acids from Ganoderma lucidum: inhibitory activity of osteoclastic differentiation and structural criteria.
Liu J, Shiono J, Shimizu K, Kondo R.
Source
Department of Forest and Forest Products Sciences, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.

Abstract
Increased osteoclastic bone resorption plays a central role in the pathogenesis of many bone diseases. Ganoderma lucidum is known for medicinal effects such as anti-inflammatory and anti-bone resorption activities. In this study, we investigated the inhibitory effects of ganoderic acids isolated from G. lucidum on osteoclastic differentiation using RAW264 cells in vitro. A carbonyl in C7 is essential to elicit the inhibition of osteoclast differentiation.

Georg Thieme Verlag KG Stuttgart . New York.

［資料來源］Liu J, et al.: Ganoderic acids from Ganoderma lucidum: inhibitory activity of osteoclastic differentiation and structural criteria. Planta Med. 2010 Feb;76(2):137-9.  
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